Two forms of the same active. B2B raw material for further formulation. Documentation and samples on request.
RAW MATERIAL · AVAILABLE FROM STOCK
What it is: A standardized xanthohumol extract from hops (Humulus lupulus L.), supplied as a yellow-orange powder. It is standardized to roughly 90 to 95% XN, and the exact content of every batch is confirmed by its own analytical report. Our reference material, for instance, was standardized to 94.7% XN. This is a standardized extract, not an isolated reference compound.
Who it is for: Supplement, nutraceutical and longevity brands developing their own formulations and premium polyphenol stacks. We supply it as a raw material for further product work, not as a finished dietary supplement.
Documentation: Each supply can come with an analytical (quantitative) report, an SDS and a product specification. The numbers describe the specific batch, not an average. Each production batch is approximately 0.5 kg. Held in stock, so there is no multi-week wait for production or import. Documentation confirms quality and parameters.
TECHNOLOGICAL FORM · MADE TO ORDER
What it is: A liposomal form of xanthohumol for teams that want a delivery-oriented format without building a liposomal system from scratch. In its native form xanthohumol is poorly water soluble, which limits how it can be worked into a product. We have a liposomal formulation developed for supplement and nutraceutical applications, designed to support stability and delivery-oriented use, and suitable for private and white label projects. The final formulation, format and regulatory status of the finished product stay with you.
To our knowledge, we are currently the only producer in Poland offering liposomal xanthohumol as a B2B raw material, rather than only as an ingredient inside its own finished product.
We produce liposomal orders individually, to order, on three principles that stay constant: our own proprietary technology, the same components, and controlled, hygienic production conditions. This avoids long storage and overproduction, and each batch is prepared as fresh as possible.
Target XN content, particle size and PDI are documented per batch and shared on request. We can also prepare the liposomal form to the parameters a given partner needs, agreed case by case.
For our reference batch and its raw materials we can provide microbiological analysis, water activity, quantitative XN content in the liposomal formulation, a TEM/DLS report with specification, SDS for the components used, and the quantitative report, specification and SDS for the source extract (standardized to 94.7% XN).
For smaller orders, we provide this full documentation package from our reference batch. If you need dedicated testing on your own material, we can prepare a made to order pilot batch with the listed tests as a separately priced package, and larger orders can include the full test package. Exact volumes and terms are agreed per project. Documentation confirms quality and parameters.
As an antioxidant it performs at the top of its class. Its free-radical neutralising capacity has been benchmarked against Trolox, the industry reference standard, and it works on two levels at once: quenching reactive species directly, and activating Nrf2/ARE, the cell's own master switch for antioxidant and cytoprotective defence.
Its anti-inflammatory signature is just as distinctive. Xanthohumol acts on the NF-κB pathway and the pro-inflammatory cytokines it drives, IL-1β, IL-6 and TNF-α, central regulators of inflammatory balance at the cellular level.
Beyond direct antioxidant action, it is also studied for activating phase II and detoxifying enzymes, such as NAD(P)H:quinone oxidoreductase and heme oxygenase-1, part of the cell's broader defence system.
And there is one catch, which is exactly where we come in. In its native form xanthohumol is poorly water soluble, which limits how much of its potential a formulation can actually use. Our liposomal form is engineered to overcome that: a delivery-oriented format built to improve the active's stability and availability, and ready for supplement and nutraceutical development, including private and white label projects.
Sources: Antioxidants (Basel) 2024;13(12):1559 — doi.org/10.3390/antiox13121559 · J Agric Food Chem 2015 — doi.org/10.1021/jf505075n · PMID 21093515 — pubmed.ncbi.nlm.nih.gov/21093515 · PMID 18952893 — pubmed.ncbi.nlm.nih.gov/18952893
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